Liverpool can take another giant step towards just a second English top-flight title in 35 years against fragile Manchester City on Sunday as Ruben Amorim aims for a first Premier League win as Manchester United manager.
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Injury-hit Arsenal have little room for error when Premier League leaders Liverpool visit the Emirates on Sunday despite losing just once so far this season.
Premier League leaders Liverpool face the first serious test of their title credentials against Chelsea this weekend as the English top flight returns after an international break.
Manchester City host Arsenal in a showdown between the Premier League title favourites on Sunday, while Tottenham boss Ange Postecoglou badly needs a win when his side host Brentford.
Liverpool boss Arne Slot faces his first major test with a trip to Manchester United, while Newcastle and Tottenham also face off on Sunday hoping to dispel early season doubts over their credentials for a top-four finish.
